October 3, 2022
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NFL odds Week 2: Opening lines for every game

Read Time:6 Minute, 29 Second

Week 2 of the NFL season offers several promising matchups on different days of the week.

Among the most intriguing games are the Chargers and Chiefs on Thursday Night Football, the Bengals and Cowboys on Sunday and the Titans and Bills on Monday Night Football.

Here’s everything you need to know about the NFL odds for Week 2 — the point spread, moneyline and total over/under (with all NFL odds via FOX Bet).           

Saquon Barkley sparks Giants’ 21-20 come back win over Titans

Saquon Barkley sparks Giants' 21-20 come back win over Titans

All times ET

THURSDAY’S GAME

Los Angeles Chargers @ Kansas City Chiefs (8:20 p.m., NBC)

Point spread: No line available
Moneyline: No line available
Total scoring over/under: No line available

SUNDAY’S GAMES

New York Jets @ Cleveland Browns (1 p.m., CBS)

Point spread: Browns -6 (Browns favored to win by more than 6 points, otherwise Jets cover)
Moneyline: Browns -278 favorites to win (bet $10 to win $13.60 total); Jets +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 42 points scored by both teams combined

New York Jets

NYJ

Cleveland Browns

CLE

Washington Commanders @ Detroit Lions (1 p.m., FOX)

Point spread: Lions -2 (Lions favored to win by more than 2 points, otherwise Commanders cover)
Moneyline: Lions -133 favorites to win (bet $10 to win $17.52 total); Commanders +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring over/under: 47 points scored by both teams combined

Washington Commanders

WAS

Detroit Lions

DET

Tampa Bay Buccaneers @ New Orleans Saints (1 p.m., FOX)

Point spread: Buccaneers -4 (Buccaneers favored to win by more than 4 points, otherwise Saints cover)
Moneyline: Buccaneers -182 favorites to win (bet $10 to win $15.49 total); Saints +140 underdogs to win (bet $10 to win $24 total)
Total scoring over/under: 46.5 points scored by both teams combined

Tampa Bay Buccaneers

TB

New Orleans Saints

NO

Carolina Panthers @ New York Giants (1 p.m., FOX)

Point spread: Giants -2 (Giants favored to win by more than 2 points, otherwise Jaguars cover)
Moneyline: Giants -133 favorites to win (bet $10 to win $17.52 total); Jaguars +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 42.5 points scored by both teams combined

Carolina Panthers

CAR

New York Giants

NYG

New England Patriots @ Pittsburgh Steelers (1 p.m., CBS)

Point spread: Patriots -1 (Patriots favored to win by more than 1 point, otherwise Steelers cover)
Moneyline: Patriots -120 favorites to win (bet $10 to win $18.33 total); Steelers -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring over/under: 41.5 points scored by both teams combined

New England Patriots

NE

Pittsburgh Steelers

PIT

Indianapolis Colts @ Jacksonville Jaguars (1 p.m., CBS)

Point spread: Colts -4 (Colts favored to win by more than 4 points, otherwise Jaguars cover)
Moneyline: Colts -213 favorites to win (bet $10 to win $14.69 total); Jaguars +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 45.5 points scored by both teams combined

Indianapolis Colts

IND

Jacksonville Jaguars

JAX

Miami Dolphins @ Baltimore Ravens (1 p.m., CBS)

Point spread: Ravens -4 (Ravens favored to win by more than 4 points, otherwise Dolphins cover)
Moneyline: Ravens -213 favorites to win (bet $10 to win $14.69 total); Dolphins +160 underdogs to win (bet $10 to win $26 total)
Total scoring over/under: 45.5 points scored by both teams combined

Miami Dolphins

MIA

Baltimore Ravens

BAL

Atlanta Falcons @ Los Angeles Rams (4:05 p.m., FOX)

Point spread: Rams -11 (Rams favored to win by more than 11 points, otherwise Falcons cover)
Moneyline: Rams -667 favorites to win (bet $10 to win $11.50 total); Falcons +400 underdogs to win (bet $10 to win $50 total)
Total scoring over/under: 48 points scored by both teams combined

Atlanta Falcons

ATL

Los Angeles Rams

LAR

Seattle Seahawks @ San Francisco 49ers (4:05 p.m., FOX)

Point spread: 49ers -9 (49ers favored to win by more than 9 points, otherwise Seahawks cover)
Moneyline: 49ers -455 favorites to win (bet $10 to win $12.20 total); Seahawks +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 42.5 points scored by both teams combined

Seattle Seahawks

SEA

San Francisco 49ers

SF

Cincinnati Bengals @ Dallas Cowboys (4:25 p.m., CBS)

Point spread: Cowboys -1.5 (Cowboys favored to win by more than 1.5 points, otherwise Bengals cover)
Moneyline: Cowboys -125 favorites to win (bet $10 to win $18 total); Bengals +100 underdogs to win (bet $10 to win $20 total)
Total scoring over/under: 50.5 points scored by both teams combined

Cincinnati Bengals

CIN

Dallas Cowboys

DAL

Houston Texans @ Denver Broncos (4:25 p.m., CBS)

Point spread: Broncos -11 (Broncos favored to win by more than 11 points, otherwise Texans cover)
Moneyline: Broncos -667 favorites to win (bet $10 to win $11.50 total); Texans +400 underdogs to win (bet $10 to win $50 total)
Total scoring over/under: 44 points scored by both teams combined

Houston Texans

HOU

Denver Broncos

DEN

Arizona Cardinals @ Las Vegas Raiders (4:25 p.m., CBS)

Point spread: Raiders -3.5 (Raiders favored to win by more than 3.5 points, otherwise Cardinals cover)
Moneyline: Raiders -175 favorites to win (bet $10 to win $15.71 total); Cardinals +135 underdogs to win (bet $10 to win $23.50 total)
Total scoring over/under: 51.5 points scored by both teams combined

Arizona Cardinals

ARI

Las Vegas Raiders

LV

Chicago Bears @ Green Bay Packers (8:20 p.m., NBC)

Point spread: Packers -9.5 (Packers favored to win by more than 9.5 points, otherwise Bears cover)
Moneyline: Packers -455 favorites to win (bet $10 to win $12.20 total); Bears +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 44.5 points scored by both teams combined

Chicago Bears

CHI

Green Bay Packers

GB

MONDAY’S GAMES

Tennessee Titans @ Buffalo Bills (7:15 p.m., ESPN)

Point spread: Bills -9.5 (Bills favored to win by more than 9.5 points, otherwise Titans cover)
Moneyline: Bills -400 favorites to win (bet $10 to win $12.50 total); Titans +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 49.5 points scored by both teams combined

Tennessee Titans

TEN

Buffalo Bills

BUF

Vikings @ Eagles (8:30 p.m. ET, ABC)

Point spread: No line available
Moneyline: No line available
Total scoring over/under: No line available

Minnesota Vikings

MIN

Philadelphia Eagles

PHI

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